Catherine Llorens-Cortes awarded with The Medal for Applications of Science 2023

Catherine Llorens-Cortes Receives Prestigious Medal for Applications of Science 2023 from the French Academy of Sciences

We are delighted to announce that Catherine Llorens-Cortes, a distinguished member of the European Academy of Sciences (EurASc), has been awarded the Medal for Applications of Science 2023 by the French Academy of Sciences. This esteemed recognition is a testament to her exceptional contributions in the field of neuropharmacology.

For over two decades, Catherine Llorens-Cortes served as the Director of the Central Laboratory of Neuropeptides and Water and Cardiovascular Regulations at the Coll├Ęge de France (Inserm U691). In 2011, her laboratory integrated into the Interdisciplinary Center for Research in Biology at CDF (Inserm U1050/CNRS 7241), solidifying her legacy of research and leadership.

Catherine’s groundbreaking work has led to the identification of novel therapeutic targets for conditions such as arterial hypertension, heart failure, and hyponatremia. These discoveries have not only advanced scientific understanding but have also paved the way for the development of various therapeutically relevant molecules.

One standout achievement is Firibastat, the first aminopeptidase A inhibitor to penetrate the brain. This innovative compound has demonstrated the ability to normalize blood pressure in various experimental hypertension models and improve cardiac function in a post-myocardial infarction heart failure model.

Clinical trials post-myocardial infarction have shown that Firibastat prevents left ventricular dysfunction with good blood pressure tolerance, showcasing the practical implications of Catherine Llorens-Cortes’s research in healthcare.

Her discovery of metabolically stable analogs of apelin, such as LIT01-196, suggests a novel approach for treating hyponatremia. Activation of the apelin receptor by this compound represents a promising avenue for addressing this condition.

EurASc takes immense pride in Catherine Llorens-Cortes’s well-deserved recognition. Her exceptional contributions to science and technology align perfectly with the mission of EurASc, and we are honored to have her as a distinguished member.

As we celebrate this achievement, we look forward to witnessing the continued impact of Catherine Llorens-Cortes’s groundbreaking research on the future of therapeutics and healthcare.

For more information about Catherine Llorens-Cortes and her contributions, please visit: https://www.college-de-france.fr/fr/actualites/catherine-llorens-cortes-laureate-2023-de-la-medaille-des-applications-des-sciences

 

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